| Place Name | Tuscumbia |
| Place Type | Town |
| ZIP Code(s) | 65082 |
| County | Miller County |
| Area Code(s) | 573 |
| Timezone | Central Standard Time (CST) |
| Population (2022) | 237 |
| Population Growth Rate (2010-19) | -7.39% |
| Majority Ethnicity | White 72.53% |
| US Congressional District(s) | Missouri 3rd |
| State House Districts | 124 |
| State Senate Districts | 6 |
| Race/Ethnicy | Percentage of Population (2021) |
|---|---|
| White | 72.53% |
| African American | 16.48% |
| Hispanic | 0% |
| Asian | 7.69% |
| Native American | 0% |
| Hawaiin/Pacific Islander | 3.3% |