| Place Name | Santee |
| Place Type | Town |
| ZIP Code(s) | 29142 |
| County | Orangeburg County |
| Area Code(s) | 803 |
| Timezone | Eastern Daylight Time (EDT) |
| Population (2022) | 946 |
| Population Growth Rate (2010-19) | -17.07% |
| Majority Ethnicity | African American 81.05% |
| Metro/Micro Stats Area | Orangeburg, SC |
| US Congressional District(s) | South Carolina 6th |
| State House Districts | 66 |
| State Senate Districts | 39 |
| Race/Ethnicy | Percentage of Population (2021) |
|---|---|
| White | 18.95% |
| African American | 81.05% |
| Hispanic | 0% |
| Asian | 0% |
| Native American | 0% |
| Hawaiin/Pacific Islander | 0% |