| Place Name | Isabel |
| Place Type | Town |
| ZIP Code(s) | 57633 |
| County | Dewey County |
| Area Code(s) | 605 |
| Timezone | Mountain Daylight Time (MDT) |
| Population (2022) | 182 |
| Population Growth Rate (2010-19) | 7.41% |
| Majority Ethnicity | White 71.74% |
| US Congressional District(s) | South Dakota At-Large |
| State House Districts | 28A |
| State Senate Districts | 28 |
| Race/Ethnicy | Percentage of Population (2021) |
|---|---|
| White | 71.74% |
| African American | 1.09% |
| Hispanic | 27.17% |
| Asian | 0% |
| Native American | 0% |
| Hawaiin/Pacific Islander | 0% |