| Place Name | Santee |
| Place Type | Village |
| ZIP Code(s) | 68760 |
| County | Knox County |
| Area Code(s) | 402,531 |
| Timezone | Central Daylight Time (CDT) |
| Population (2022) | 343 |
| Population Growth Rate (2010-19) | 22.54% |
| Majority Ethnicity | Native American 0.29% |
| US Congressional District(s) | Nebraska 3rd |
| State Legislature Districts | 40 |
| Race/Ethnicy | Percentage of Population (2021) |
|---|---|
| White | 4.07% |
| African American | 0.58% |
| Hispanic | 84.88% |
| Asian | 0.29% |
| Native American | 0.29% |
| Hawaiin/Pacific Islander | 9.88% |