| Place Name | De Soto |
| Place Type | Village |
| ZIP Code(s) | 54624 |
| GEOID | 5519850 |
| County | Vernon County |
| Area Code(s) | 608 |
| Timezone | Central Standard Time (CST) |
| Population (2021) | 549 |
| Population Growth Rate (2010-19) | 7.67% |
| Majority Ethnicity | White 99.27% |
| US Congressional District(s) | Wisconsin 3rd |
| State Assembly Districts | 96 |
| State Senate Districts | 32 |
| Race/Ethnicy | Percentage of Population (2021) |
|---|---|
| White | 99.27% |
| African American | 0% |
| Hispanic | 0% |
| Asian | 0% |
| Native American | 0% |
| Hawaiin/Pacific Islander | 0.73% |