This table ranks all 22 ZIP codes in the Adrian, MI MSA by estimated 2022 population, from highest to lowest.
| # | ZIP Code | Place Name | Population (2022) |
|---|---|---|---|
| 1 | ZIP 49221 | Adrian | 41,209 |
| 2 | ZIP 49286 | Tecumseh | 14,624 |
| 3 | ZIP 49230 | Brooklyn | 10,089 |
| 4 | ZIP 49247 | Hudson | 5,427 |
| 5 | ZIP 49228 | Blissfield | 5,381 |
| 6 | ZIP 49265 | Onsted | 5,129 |
| 7 | ZIP 49236 | Clinton | 5,036 |
| 8 | ZIP 49267 | Ottawa Lake | 4,024 |
| 9 | ZIP 49256 | Morenci | 3,694 |
| 10 | ZIP 49229 | Britton | 3,378 |
| 11 | ZIP 49233 | Cement City | 2,889 |
| 12 | ZIP 49220 | Addison | 2,795 |
| 13 | ZIP 49253 | Manitou Beach | 2,676 |
| 14 | ZIP 49287 | Tipton | 2,099 |
| 15 | ZIP 49235 | Clayton | 2,059 |
| 16 | ZIP 49238 | Deerfield | 1,945 |
| 17 | ZIP 49288 | Waldron | 1,518 |
| 18 | ZIP 49268 | Palmyra | 1,179 |
| 19 | ZIP 49279 | Sand Creek | 889 |
| 20 | ZIP 49248 | Jasper | 883 |
| 21 | ZIP 49276 | Riga | 873 |
| 22 | ZIP 49289 | Weston | 81 |