This table ranks all 26 ZIP codes in the Syracuse, NY MSA by estimated 2022 population, from highest to lowest.
| # | ZIP Code | Place Name | Population (2022) |
|---|---|---|---|
| 1 | ZIP 13021 | Auburn | 37,640 |
| 2 | ZIP 13126 | Oswego | 36,278 |
| 3 | ZIP 13045 | Cortland | 28,157 |
| 4 | ZIP 13152 | Skaneateles | 7,700 |
| 5 | ZIP 13077 | Homer | 6,646 |
| 6 | ZIP 13073 | Groton | 6,514 |
| 7 | ZIP 13118 | Moravia | 5,811 |
| 8 | ZIP 13166 | Weedsport | 5,758 |
| 9 | ZIP 13074 | Hannibal | 4,453 |
| 10 | ZIP 13140 | Port Byron | 4,335 |
| 11 | ZIP 14882 | Lansing | 3,678 |
| 12 | ZIP 13033 | Cato | 3,661 |
| 13 | ZIP 13080 | Jordan | 3,519 |
| 14 | ZIP 13092 | Locke | 2,726 |
| 15 | ZIP 13143 | Red Creek | 2,354 |
| 16 | ZIP 13160 | Union Springs | 2,262 |
| 17 | ZIP 13156 | Sterling | 2,169 |
| 18 | ZIP 13034 | Cayuga | 2,022 |
| 19 | ZIP 13111 | Martville | 1,790 |
| 20 | ZIP 13026 | Aurora | 1,737 |
| 21 | ZIP 13024 | Auburn | 1,380 |
| 22 | ZIP 13081 | King Ferry | 1,114 |
| 23 | ZIP 13147 | Scipio Center | 929 |
| 24 | ZIP 13071 | Genoa | 864 |
| 25 | ZIP 13117 | Montezuma | 279 |
| 26 | ZIP 13113 | Meridian | 52 |