This table ranks all 16 ZIP codes in the Poplar Bluff, MO MSA by estimated 2022 population, from highest to lowest.
| # | ZIP Code | Place Name | Population (2022) |
|---|---|---|---|
| 1 | ZIP 63901 | Poplar Bluff | 34,545 |
| 2 | ZIP 63935 | Doniphan | 8,002 |
| 3 | ZIP 63937 | Ellsinore | 2,542 |
| 4 | ZIP 63966 | Wappapello | 2,117 |
| 5 | ZIP 63961 | Qulin | 1,853 |
| 6 | ZIP 63967 | Williamsville | 1,609 |
| 7 | ZIP 63940 | Fisk | 1,419 |
| 8 | ZIP 63939 | Fairdealing | 1,190 |
| 9 | ZIP 63945 | Harviell | 1,090 |
| 10 | ZIP 63932 | Broseley | 1,012 |
| 11 | ZIP 63954 | Neelyville | 946 |
| 12 | ZIP 63943 | Grandin | 862 |
| 13 | ZIP 63953 | Naylor | 803 |
| 14 | ZIP 63942 | Gatewood | 487 |
| 15 | ZIP 63962 | Rombauer | 181 |
| 16 | ZIP 63955 | Oxly | 86 |