| District Name | Picayune School District |
| State | Mississippi |
| County | Pearl River County Hancock County |
| Statistical Area | Picayune, MS:picayune-ms Picayune, MS:picayune-ms |
| Cities/Towns | |
| Total Students (2021) | 3192 |
| District Growth Rate (2017-21) | -11.7% |
| Majority Race/Ethnicty | White (57.3%) |
| Free/Reduced Lunch Program | 100% |