| District Name | Nell Holcomb R-IV School District |
| State | Missouri |
| County | Cape Girardeau County |
| Statistical Area | Cape Girardeau, MO-IL |
| Total Students (2021) | 232 |
| District Growth Rate (2017-21) | -14.7% |
| Majority Race/Ethnicty | White (91.0%) |
| Free/Reduced Lunch Program | 43.97% |