| District Name | Natalia Independent School District |
| State | Texas |
| County | Medina County |
| Statistical Area | San Antonio-New Braunfels, TX |
| Cities/Towns | Natalia |
| Total Students (2021) | 1024 |
| District Growth Rate (2017-21) | -5.6% |
| Majority Race/Ethnicty | Hispanic (83.0%) |
| Free/Reduced Lunch Program | 76.27% |