| District Name | San Isidro Independent School District |
| State | Texas |
| County | Starr County |
| Statistical Area | Rio Grande City-Roma, TX |
| Total Students (2021) | 197 |
| District Growth Rate (2017-21) | -19.3% |
| Majority Race/Ethnicty | Hispanic (100.0%) |
| Free/Reduced Lunch Program | 96.95% |