| Place Name | Brussels |
| Place Type | Village |
| ZIP Code(s) | 62013 |
| County | Calhoun County |
| Area Code(s) | 618 |
| Timezone | Central Daylight Time (CDT) |
| Population (2022) | 151 |
| Population Growth Rate (2010-19) | -17.73% |
| Majority Ethnicity | White 98.51% |
| Metro/Micro Stats Area | St. Louis, MO-IL |
| US Congressional District(s) | Illinois 13th |
| State House Districts | 100 |
| State Senate Districts | 50 |
| Race/Ethnicy | Percentage of Population (2021) |
|---|---|
| White | 98.51% |
| African American | 0% |
| Hispanic | 0% |
| Asian | 0% |
| Native American | 0% |
| Hawaiin/Pacific Islander | 1.49% |