ZIP Code 54221 is located in Manitowoc Wisconsin. 54221 is entirely within Manitowoc County. Regionally, it is located in the Green Bay-Appleton Area.
| ZIP Code Name | Manitowoc |
| Primary County | Manitowoc County |
| ZIP Code Type | PO Box |
| Current Time | CDT |
| Coordinates | 44.09006500,-87.66333008 |
| Adjacent ZIP Codes | |
| Region | Green Bay-Appleton Area |
| Metropolitan/Micropolitan Stat Area | Manitowoc, WI |
| Time Zone | Central Daylight Time |
| IANA Timezone | America/Chicago |